Ok, i'm going to assume you know what ascension is. If you don't, go look it up on the kolwiki, there are tons of pages on ascension, what it is, and many "strategies" for it. The goal here is to give our dear n00bz a very *basic* guide.
A lot of people have asked me this question lately, so i'm adding the answer here...
Q:
If i buy a skill after freeing the king, will it still be HP when i ascend?A: As long as you purchase a skill *before* you ascend, it is yours to keep (if you select it)
no matter when you free the king!
Replies concerning speed runs are not welcome here. Create your own thread for that, don't jack mine please and thank you

Replies, comments, suggestions, questions concerning the topic of
this thread are most welcome here. Now, on to the good stuff!
1) Wether you want to do hardcore or softcore, i highly recommend your first run be softcore (keep in mind a skill you would like to have when returning to a softcore run
http://kol.coldfront.net/thekolwiki/index.php/Skills_by_number so if you do choose to do hardcore, you can select a skill you *won't* pick up in your hardcore runs).
2) Sign, mongoose, for two reasons. a) free stat points are always good, and b) the opportunity to use the mushroom plot and get yourself 3 new elemental gravy fairies, one of which has a familiar item that drops in the sleazy back alley (
http://kol.coldfront.net/thekolwiki/index.php/Sleazy_Gravy_Fairy ) which, granted, is more important if you want to do hardcore and do not have access to Mr. Store familiars.
3) Path...teet/booze run level requirements now make the "reward" kind of a moot point. If you need spare meat, try a boozy run, the whiskey usually fetches a fair price in the mall. Oxygenarian...one run in each class for all the shinies, then done! Unless you're a masochist, or short on time, i do *not* recommend going oxy without a metric butt-ton of banked HP skills.
To recap: Hardcore = any class, mongoose. Softcore = any class, no path, mongoose!
4) When you ascend from your first softcore into your first hardcore i highly recommend sauceror, marmot or opposum! Why? You get more stats from food than booze, simple. For your second hardcore run i recommend pastamancer. Your first two hardcore runs will be for the level 5 summoning skills (reagents, then noodles). Wait!! Isn't that backward?! *No*! Ok, but...*why* isn't that backward? Let me enlighten you

Until you have the reagent skill, the pasta dishes you can make *suck*. Badly. Yes, your sauce run will be long (not nearly as long as an oxy run), but, the ability to make reagent potions can save your butt against bosses, and shave a few days off your total run-time. Tomatoes and olives are your friends, kids!
If you are doing hardcore...stay no path, even without the cocktail crafting skills! You'll pick up booze along the way during your run, and even if it isn't *good* booze, it's more adventures!
If you are doing softcore...take the time to meat/item farm for things you will need in your softcore runs. Chefbot (
http://forums.kingdomofloathing.com/viewtopic.php?t=24186 ) can take your reagents and glasses of goat's milk and make you milk of magnesium. She can also take your base booze and corresponding cocktail accessory (ie: whiskey sour and coconut shell) and make you 4D disco bandit drinks! Huzzah! If you are operating on a limited budget, she can also make you reagent foods (you can farm the items yourself). One of these days i'll get around to making a list of items to have before ascending softcore.
i do try to check the forum as often as possible, be patient and bear with me if i miss your post for a while...we have vicious attack reindeer up here...
NS13 tips...cry. cry some more. now sit back, relax, and listen to the pearls of wisdom from aunty snooty XD No wait, cry some more! A hardcore life in ns13 has become, well, harder. Not insurmountably so, but, your runs will be slower if you're used to ns11. If you have a pixie, huzzah! Abuse that little sucker for booze/spleen items as often as you can! If you don't, cry some more.
Ok, now that we've worked out the tears...the lower levels are honestly going to be a bit on the painful side. You are going to have to suck it up, and eat things you never considered as more than an autosell-free-meat-in-hc bonus. Ditto on the booze front. Wait, what? Where's the silver lining? The light at the end of the tunnel? Here it is, and, it isn't much...the best thing you can do for yourself (aside from using your stat fam as often as possible) is to use your +meat/item fams as often as possible pre-level 12. The quickest way to get to face the ns and free the king = do the hippy sidequests, and forget about the wossname. With a fat +meat fam, the nun's quest really doesn't take very long, especially if you manage to pick up an inhaler at the castle. You'll want a decently heavy item fam for the orchard quest (and we all need items in a run anyway).
Quicker way through the dooks? Who'd want *that*?!?! In case you do, use a chaos butterfly in between the castle and the farm, then choose fence-lantern-drum (pond, back 40, other back 40).
Update!
Want to 1hk your shadow? Yeah, thought you might

Take the time to get massage oil
http://kol.coldfront.net/thekolwiki/index.php/Semi-Rare_Adventures in the harem. Boost your hp as much as possible, but go in to face the shadow with about a third of your hp. Yes, you will lose initiative, you want to! As long as you have at least 1hp left from the shadow's first hit (and you should), toss a massage oil for supremely sexy one-hit victory!
That's it for now til i have time to actually read and catch up on stuff, g'luck!
Effortless gloomies scripting!The link should automatically download the script "MaxShrooms.ash". You'll need to go into mafia - setttings - find your preference text file, and adjust the planting info below the link. Check the "plant shrooms" option in breakfast settings. The script itself needs to reside within the mafia "planting" folder.
http://kolmafia.us/index.php?action=dlattach;topic=783.0;attach=1912plantingDate=0
plantingDay=8
plantingLength=16
plantingScript=MaxShrooms
In case there are problems with the first link, this one is to the original topic at the script repository. Scroll down to the bottom and look for Sandiman's last post, he's the author of this shroom script. Enjoy!
http://kolmafia.us/index.php/topic,783.0.html